Enteric Micro-Particles for Targeted Oral Drug Delivery

Advances in Targeted Drug Delivery

Advances in Targeted Drug Delivery

Oral Micro-particulate Colon Targeted Drug Delivery System for the Treatment of Crohn's Disease: a Review

Crohn's disease is thought to be an autoimmune disease, in which the body's immune system attacks the gastrointestinal tract, causing inflammation, it is classified as a type of inflammatory bowel disease. The microspheres carrier for the delivery of the dosage form to the colon is composed of physiological and biodegradable natural polysaccharides and which in turn cause low systemic toxicity,...

Modern prodrug design for targeted oral drug delivery.

The molecular information that became available over the past two decades significantly influenced the field of drug design and delivery at large, and the prodrug approach in particular. While the traditional prodrug approach was aimed at altering various physiochemical parameters, e.g., lipophilicity and charge state, the modern approach to prodrug design considers molecular/cellular factors, ...

Nanoscale Metal Particles as Nanocarriers in Targeted Drug Delivery System

Submit Manuscript | http://medcraveonline.com release process [1-8]. The comfort factors in using nanoscale metal particles are attained from their capability to increase the aqueous solubility of hydrophobic drugs compound, enhanced the circulation time of drugs in the blood, and repress or eliminate fast renal drugs excretion. Nevertheless, the clinical success of these agents is crucially re...